for Genomic Regulation (CRG) is an international biomedical research institute
of excellence, based in Barcelona, Spain, with more than 400 scientists from 44
countries. The CRG shares principles of an interdisciplinary, motivated and
creative scientific team that is supported by high-end and innovative
technologies and a flexible and efficient administration.
been conferred with a badge of ‘HR Excellence in Research’ by the European
Commission, in recognition to its progress in implementing the European Charter
for Researchers and the Code of Conduct for Recruitment of Researchers, that
among others consists of transparent, merit-based recruitment procedures and
attractive work-life balance working conditions.
framework of the 4DGenome project we are seeking for a bioinformatician for the
management and analysis of high-throughput sequencing data (mainly Hi-C,
ChIP-Seq and RNA-Seq).
responsibilities of the candidate will be:
● Process the sequencing data
generated in the 4DGenome with the existing analysis workflows
● Implementation of computational
pipelines and development of interactive web applications to automate the
analysis and visualisation of large genomic datasets
● Provide data analysis support to
members of the project to facilitate the interpretation of the results and
● Sustain the team culture of
documentation, automation, data traceability and autonomy for the experimenters
About the project
4DGenome project (ERC Synergy 609989) brings together 4 multi-disciplinary
groups from the CRG/CNAG (Miguel Beato, Thomas Graf, Marc Marti-Renom and
Guillaume Filion) which aim at analyzing the changes in the 3D organization of
the genome during induced stable cell fate changes and transient hormonal
response. Fulfilling such objective requires the production of high quality,
high coverage datasets of genome-wide spatial contacts in an important amount
of cell types and conditions. All the sequencing data are processed through a
dedicated pipeline developed in house to facilitate sample tracking, analysis
and data release.
Whom would we like to hire?
● You hold a Phd or MSc degree in
Bioinformatics or related field.
● You have experience with the
management and analysis of high-throughput sequencing data.
● Proficient in the cleaning,
processing and quantitative analysis of genomics data
● Experienced in the use of
Unix/Linux environments and HPC systems
● Shell scripting, Python and R are
highly required; use of Git for software version control is needed
● Knowledge of common bioinformatics
tools is required (e.g. mappers, peak callers, differential expression analysis
● Use of tools to comply with the
reproducibility of the analyses will be highly valued (e.g. Jupyter notebooks,
● Familiarity with SQL databases and
tools for the development of web applications (e.g. R Shiny) will be a plus
● You are fluent in English
● Contract duration: 1 year, with an
option to be extended
● Estimated annual gross salary:
Salary is commensurate with qualifications and consistent with our pay scales.
● Target start date: As soon as
a highly stimulating environment with state-of-the-art infrastructures, and
unique professional career development opportunities.
and promote a diverse and inclusive environment and welcomes applicants
regardless of age, disability, gender, nationality, race, religion or sexual
committed to reconcile a work and family life for our employees and are
offering the opportunity to benefit from annual leave, flexible working hours
applications must include:
1. A motivation letter addressed to Dr.
2. A complete CV including contact
3. Contact details of two referees.
applications must be addressed to Dr. Miguel Beato and be submitted online on
the on the CRG Career site -
Please submit your application by the 11th of February 2018
grant agreement 609989 (4DGenome)