The commitment of the Universiat de Barcelona (UB, University of Barcelona) to strengthening its role in the public sector, by returning to society the benefits of its scientific and technological expertise, is one of the reasons behind the decision to set up the "Science Park", taken at the extraordinary meeting of the Governing Body of the UB on 17 November 1994.

On 26 September 1997, the President of the Generalitat de Catalunya (Autonomous Government of Catalonia), Jordi Pujol, presided over the constitution of the Fundació Parc Científic de Barcelona (PCB Foundation) by the UB, the Bosch i Gimpera Foundation and the Caixa Catalunya. The Foundation was created to oversee the implementation of the PCB project.

The Board of the PCB Foundation works closely with a Scientific Committee, which offers advice, and evaluates and monitors the research conducted in the Park, mainly with regard to the IRB project.